中文名 | KF31327 free base |
英文名 | Thioquinapiperifil |
别名 | 硫喹哌非 西地那非杂质35 化合物 T26273 |
英文别名 | KF31327 Thioquinapiperfil KF31327 free base Thioquinapiperifil KF-31327 free base 3-ethyl-8-[[2-[4-(hydroxymethyl)piperidin-1-yl]phenyl]methylamino]-1H-imidazo[4,5-g]quinazoline-2-thione 2H-Imidazo[4,5-g]quinazoline-2-thione, 3-ethyl-1,3-dihydro-8-[[[2-[4-(hydroxymethyl)-1-piperidinyl]phenyl]methyl]amino]- |
CAS | 220060-39-9 |
化学式 | C24H28N6OS |
分子量 | 448.58 |
存储条件 | 2-8°C,密封,干燥 |
体外研究 | Thioquinapiperifil can be found in dietary supplements. Thioquinapiperifil (KF31327 free base) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil (KF31327 free base) are required to inhibit platelet aggregation. Thioquinapiperifil (KF31327 free base) and shows significant increase in cyclic GMP at 10 μM. After 5 min incubation, the mean cyclic GMP levels of Thioquinapiperifil (KF31327)-treated cells is 0.95±0.17 pmol/10 8 cells. |